Generation of a Cell Culture-Adapted Hepatitis C Virus with Longer Half Life at Physiological Temperature
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منابع مشابه
Generation of a Cell Culture-Adapted Hepatitis C Virus with Longer Half Life at Physiological Temperature
BACKGROUND We previously reported infectious HCV clones that contain the convenient reporters, green fluorescent protein (GFP) and Renilla luciferase (Rluc), in the NS5a-coding sequence. Although these viruses were useful in monitoring viral proliferation and screening of anti-HCV drugs, the infectivity and yield of the viruses were low. METHODOLOGY/PRINCIPAL FINDINGS In order to obtain a hig...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0022808